R-loopReGSEA

R-loopReGSEA is an online tool to determine whether R-loop regulators are significantly enriched or depleted under specific genetic or experimental perturbations by gene set enrichment analysis (GSEA), as an indication of dysregulation of R-loop homeostasis.

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1. Please provide the content of the file to be analyzed:

Please enter tab-delimited data with a header and at least two columns. The first column may contain gene identifiers such as Entrez ID, Ensembl ID or gene symbol. (Note: Because genes can have multiple aliases, the use of gene symbols is not recommended.) The second and subsequent columns should represent values such as log2FoldChange.

2. Or you can upload a tab-delimited text file.

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Download example file

Upload a tab-delimited file or paste text directly, then submit the analysis.

Result Display

After submission, you can preview and download all analysis results. Clicking on a gene symbol of interest will direct you to the corresponding regulator page, where detailed information about that gene is provided.