Transcription Track Settings

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Transcription (All R-loopBase Data tracks)

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	Cell Line^↓1	Technology^↓2	Treatment^↓3	Strand^↓4	Track Name^↓5
full Configure	HEK293T	GRO-seq	Control	fwd	HEK293T_Control_GRO-seq.fwd	Schema
full Configure	HEK293T	GRO-seq	Control	rev	HEK293T_Control_GRO-seq.rev	Schema
full Configure	HEK293T	PRO-seq	Control	fwd	HEK293T_Control_PRO-seq.fwd	Schema
full Configure	HEK293T	PRO-seq	Control	rev	HEK293T_Control_PRO-seq.rev	Schema
full Configure	HeLa	GRO-seq	Control	fwd	HeLa_Control_GRO-seq.fwd	Schema
full Configure	HeLa	GRO-seq	Control	rev	HeLa_Control_GRO-seq.rev	Schema
full Configure	HeLa	PRO-seq	Control	fwd	HeLa_Control_PRO-seq.fwd	Schema
full Configure	HeLa	PRO-seq	Control	rev	HeLa_Control_PRO-seq.rev	Schema
full Configure	hESCs	GRO-seq	Control	fwd	hESCs_Control_GRO-seq.fwd	Schema
full Configure	hESCs	GRO-seq	Control	rev	hESCs_Control_GRO-seq.rev	Schema
full Configure	K562	GRO-seq	Control	fwd	K562_Control_GRO-seq.fwd	Schema
full Configure	K562	GRO-seq	Control	rev	K562_Control_GRO-seq.rev	Schema
full Configure	MCF-7	GRO-seq	Control	fwd	MCF7_Control_GRO-seq.fwd	Schema
full Configure	MCF-7	GRO-seq	Control	rev	MCF7_Control_GRO-seq.rev	Schema

Description

GRO-seq (Global Run-On sequencing) and PRO-seq (Precision Run-On sequencing) capture nascent RNA by labeling and sequencing actively elongating RNA polymerases, providing a high-resolution, strand-specific map of ongoing transcription. Since R-loop formation is coupled to active transcription, regions with high nascent RNA output are frequently hotspots for R-loop formation.