ID:BRD1_HUMAN DESCRIPTION: RecName: Full=Bromodomain-containing protein 1; AltName: Full=BR140-like protein; AltName: Full=Bromodomain and PHD finger-containing protein 2; FUNCTION: Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. SUBUNIT: Component of the MOZ/MORF complex composed at least of ING5, KAT6A, KAT6B, MEAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3. Interacts (via PHD-type zinc finger domain) with unmodified histone H3. Interacts (via PWWP domain) with dimethylated and trimethylated 'Lys-79' on histone H3. SUBCELLULAR LOCATION: Nucleus. TISSUE SPECIFICITY: Highly expressed in testis. SIMILARITY: Contains 1 bromo domain. SIMILARITY: Contains 1 PHD-type zinc finger. SIMILARITY: Contains 1 PWWP domain.
Protein Domain and Structure Information
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Other Names for This Gene
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Methods, Credits, and Use Restrictions
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