Human Gene EMCN (ENST00000296420.9) Description and Page Index

Description: Homo sapiens endomucin (EMCN), transcript variant 1, mRNA. (from RefSeq NM_016242)
Gencode Transcript: ENST00000296420.9
Gencode Gene: ENSG00000164035.10
Transcript (Including UTRs)
Position: hg38 chr4:100,395,341-100,518,022 Size: 122,682 Total Exon Count: 12 Strand: -
Coding Region
Position: hg38 chr4:100,410,321-100,517,914 Size: 107,594 Coding Exon Count: 11

Page Index

Sequence and Links

UniProtKB Comments

Protein Structure

Other Names

Methods

Data last updated at UCSC: 2021-06-20 19:51:40

Comments and Description Text from UniProtKB


	ID: MUCEN_HUMAN DESCRIPTION: RecName: Full=Endomucin; AltName: Full=Endomucin-2; AltName: Full=Gastric cancer antigen Ga34; AltName: Full=Mucin-14; Short=MUC-14; Flags: Precursor; FUNCTION: Endothelial sialomucin, also called endomucin or mucin- like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. SUBCELLULAR LOCATION: Isoform 1: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Note=Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks. SUBCELLULAR LOCATION: Isoform 2: Secreted (Potential). TISSUE SPECIFICITY: Expressed in heart, kidney and lung. PTM: Highly O-glycosylated. Sialic acid-rich glycoprotein.