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Comments and Description Text from UniProtKB
ID:FGF17_HUMAN DESCRIPTION: RecName: Full=Fibroblast growth factor 17; Short=FGF-17; Flags: Precursor; FUNCTION: Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development. SUBUNIT: Interacts with FGFR3 and FGFR4. SUBCELLULAR LOCATION: Secreted. TISSUE SPECIFICITY: Preferentially expressed in the embryonic brain. DEVELOPMENTAL STAGE: Detected in embryos at E14.5, but not at E10.5 and E19.5. Preferentially expressed in the neuroepithelia of the isthmus and septum of the embryonic brain at E14.5. SIMILARITY: Belongs to the heparin-binding growth factors family. WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/fgf17/";
Protein Domain and Structure Information
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