Human Gene MTAP (ENST00000580900.5) Description and Page Index
Description: Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates. (from UniProt Q13126) Gencode Transcript: ENST00000580900.5 Gencode Gene: ENSG00000099810.21 Transcript (Including UTRs) Position: hg38 chr9:21,802,649-21,937,651 Size: 135,003 Total Exon Count: 8 Strand: + Coding Region Position: hg38 chr9:21,802,749-21,931,199 Size: 128,451 Coding Exon Count: 8
ModBase Predicted Comparative 3D Structure on Q13126
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Other Names for This Gene
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Methods, Credits, and Use Restrictions
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