Human Gene EGFR (ENST00000342916.7) Description and Page Index
  Description: Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 2, mRNA. (from RefSeq NM_201282)
Gencode Transcript: ENST00000342916.7
Gencode Gene: ENSG00000146648.19
Transcript (Including UTRs)
   Position: hg38 chr7:55,019,032-55,168,635 Size: 149,604 Total Exon Count: 16 Strand: +
Coding Region
   Position: hg38 chr7:55,019,278-55,168,529 Size: 149,252 Coding Exon Count: 16 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther NamesMethods
Data last updated at UCSC: 2021-06-20 19:51:40

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:55,019,032-55,168,635)mRNA (may differ from genome)Protein (628 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaExonPrimerGeneCards
HGNCMGIPubMedUniProtKB

+  Comments and Description Text from UniProtKB
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-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000494 - EGF_rcpt_L
IPR006211 - Furin-like_Cys-rich_dom
IPR006212 - Furin_repeat
IPR009030 - Growth_fac_rcpt
IPR011009 - Kinase-like_dom
IPR000719 - Prot_kinase_cat_dom
IPR017441 - Protein_kinase_ATP_BS
IPR001245 - Ser-Thr/Tyr_kinase_cat_dom
IPR008266 - Tyr_kinase_AS
IPR020635 - Tyr_kinase_cat_dom
IPR016245 - Tyr_kinase_EGF/ERB/XmrK_rcpt

Pfam Domains:
PF00757 - Furin-like cysteine rich region
PF07714 - Protein tyrosine kinase
PF01030 - Receptor L domain

Protein Data Bank (PDB) 3-D Structure
MuPIT help

1DNQ
- Model

1DNR
- Model

1IVO
- X-ray
To conserve bandwidth, only the images from the first 3 structures are shown.
1M14 - X-ray 1M17 - X-ray 1MOX - X-ray
1NQL - X-ray 1XKK - X-ray 1YY9 - X-ray
1Z9I - NMR 2EB2 - X-ray 2EB3 - X-ray
2EXP - Model 2EXQ - Model 2GS2 - X-ray
2GS6 - X-ray 2GS7 - X-ray 2ITN - X-ray
2ITO - X-ray 2ITP - X-ray 2ITQ - X-ray
2ITT - X-ray 2ITU - X-ray 2ITV - X-ray
2ITW - X-ray 2ITX - X-ray 2ITY - X-ray
2ITZ - X-ray 2J5E - X-ray 2J5F - X-ray
2J6M - X-ray 2JIT - X-ray 2JIU - X-ray
2JIV - X-ray 2KS1 - NMR 2RF9 - X-ray
2RFD - X-ray 2RFE - X-ray 2RGP - X-ray
3B2U - X-ray 3B2V - X-ray 3BEL - X-ray
3BUO - X-ray 3C09 - X-ray 3G5V - X-ray
3G5Y - X-ray 3GOP - X-ray 3GT8 - X-ray
3IKA - X-ray 3LZB - X-ray 3NJP - X-ray
3OB2 - X-ray 3OP0 - X-ray 3P0Y - X-ray
3PFV - X-ray 3POZ - X-ray 3QWQ - X-ray
3UG1 - X-ray 3UG2 - X-ray 3VJN - X-ray
3VJO - X-ray 4G5J - X-ray 4G5P - X-ray


ModBase Predicted Comparative 3D Structure on P00533
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+  Other Names for This Gene
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-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.