Human Gene RPS6 (ENST00000380394.9) Description and Page Index
  Description: Homo sapiens ribosomal protein S6 (RPS6), mRNA. (from RefSeq NM_001010)
Gencode Transcript: ENST00000380394.9
Gencode Gene: ENSG00000137154.13
Transcript (Including UTRs)
   Position: hg38 chr9:19,375,715-19,380,236 Size: 4,522 Total Exon Count: 6 Strand: -
Coding Region
   Position: hg38 chr9:19,376,293-19,380,195 Size: 3,903 Coding Exon Count: 6 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther NamesMethods
Data last updated at UCSC: 2021-06-20 19:51:40

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr9:19,375,715-19,380,236)mRNA (may differ from genome)Protein (249 aa)
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-  Comments and Description Text from UniProtKB
  ID: RS6_HUMAN
DESCRIPTION: RecName: Full=40S ribosomal protein S6; AltName: Full=Phosphoprotein NP33;
FUNCTION: May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.
INTERACTION: Q09161:NCBP1; NbExp=3; IntAct=EBI-356625, EBI-464743;
PTM: Ribosomal protein S6 is the major substrate of protein kinases in eukaryote ribosomes. The phosphorylation is stimulated by growth factors, tumor promoting agents, and mitogens. It is dephosphorylated at growth arrest. Phosphrylated at Ser-235 and Ser-236 by RPS6KA1 and RPS6KA3; phosphorylation at these sites facilitates the assembly of the preinitiation complex.
SIMILARITY: Belongs to the ribosomal protein S6e family.

+  Protein Domain and Structure Information
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+  Other Names for This Gene
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-  Methods, Credits, and Use Restrictions
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