Human Gene EMCN (ENST00000296420.9) Description and Page Index
  Description: Homo sapiens endomucin (EMCN), transcript variant 1, mRNA. (from RefSeq NM_016242)
Gencode Transcript: ENST00000296420.9
Gencode Gene: ENSG00000164035.10
Transcript (Including UTRs)
   Position: hg38 chr4:100,395,341-100,518,022 Size: 122,682 Total Exon Count: 12 Strand: -
Coding Region
   Position: hg38 chr4:100,410,321-100,517,914 Size: 107,594 Coding Exon Count: 11 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther NamesMethods
Data last updated at UCSC: 2021-06-20 19:51:40

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:100,395,341-100,518,022)mRNA (may differ from genome)Protein (261 aa)
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HGNCMGIPubMedUniProtKB

-  Comments and Description Text from UniProtKB
  ID: MUCEN_HUMAN
DESCRIPTION: RecName: Full=Endomucin; AltName: Full=Endomucin-2; AltName: Full=Gastric cancer antigen Ga34; AltName: Full=Mucin-14; Short=MUC-14; Flags: Precursor;
FUNCTION: Endothelial sialomucin, also called endomucin or mucin- like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
SUBCELLULAR LOCATION: Isoform 1: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Note=Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.
SUBCELLULAR LOCATION: Isoform 2: Secreted (Potential).
TISSUE SPECIFICITY: Expressed in heart, kidney and lung.
PTM: Highly O-glycosylated. Sialic acid-rich glycoprotein.

+  Protein Domain and Structure Information
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+  Other Names for This Gene
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-  Methods, Credits, and Use Restrictions
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