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Comments and Description Text from UniProtKB
ID:TMIG2_HUMAN DESCRIPTION: RecName: Full=Transmembrane and immunoglobulin domain-containing protein 2; AltName: Full=Immunoglobulin and proline-rich receptor 1; Short=IGPR-1; Flags: Precursor; FUNCTION: Plays a role in cell-cell interaction, cell migration, and angiogenesis. SUBUNIT: May form homophilic interactions that could regulate cell-cell interaction. Interacts with CACNB2, DST, MIA and NCKIPSD. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Widely expressed, mainly by epithelial and endothelial cells, including bronchial epithelial cells of lung, breast glandular and lobular epithelia cells, urothelium of the bladder, skin epidermis, epithelium of gastrointestinal, rectum, endometrial glands of the uterus, ureter, fallopian tube epithelium, colonic epithelium, small bowl epithelium, stomach epithelium, including both chief and parietal cells, trophoblastic epithelium of placenta, and pancreatic acinar cells (at protein level). Consistently expressed in veins and arteries (at protein level). Not detected in thyroid, cerebellum, cerebral cortex and thymus (at protein level). PTM: N-glycosylated. SIMILARITY: Contains 1 Ig-like (immunoglobulin-like) domain.
Protein Domain and Structure Information
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Other Names for This Gene
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.
