Human Gene KCNAB2 (ENST00000352527.6) Description and Page Index

Description: Homo sapiens potassium voltage-gated channel subfamily A regulatory beta subunit 2 (KCNAB2), transcript variant 2, mRNA. (from RefSeq NM_172130)
Gencode Transcript: ENST00000352527.6
Gencode Gene: ENSG00000069424.15
Transcript (Including UTRs)
Position: hg38 chr1:6,026,163-6,101,178 Size: 75,016 Total Exon Count: 15 Strand: +
Coding Region
Position: hg38 chr1:6,040,569-6,098,574 Size: 58,006 Coding Exon Count: 14

Page Index

Sequence and Links

UniProtKB Comments

Protein Structure

Other Names

Methods

Data last updated at UCSC: 2021-06-20 19:51:40

Comments and Description Text from UniProtKB


	ID: KCAB2_HUMAN DESCRIPTION: RecName: Full=Voltage-gated potassium channel subunit beta-2; AltName: Full=K(+) channel subunit beta-2; AltName: Full=Kv-beta-2; Short=hKvbeta2; FUNCTION: Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters functional properties of Kv1.4. SUBUNIT: Forms heteromultimeric complex with alpha subunits. Forms a ternary complex with SQSTM1 and PRKCZ (By similarity). SUBCELLULAR LOCATION: Cytoplasm (Potential). DOMAIN: Alteration of functional properties of alpha subunit is mediated through N-terminal domain of beta subunit (Probable). PTM: Phosphorylated by PRKCZ; may be regulated by incorporation in a complex composed of PRKCZ and SQSTM1 (By similarity). SIMILARITY: Belongs to the shaker potassium channel beta subunit family.