Human Gene GFRA2 (ENST00000524240.6) Description and Page Index
  Description: Homo sapiens GDNF family receptor alpha 2 (GFRA2), transcript variant 1, mRNA. (from RefSeq NM_001495)
Gencode Transcript: ENST00000524240.6
Gencode Gene: ENSG00000168546.11
Transcript (Including UTRs)
   Position: hg38 chr8:21,690,398-21,788,875 Size: 98,478 Total Exon Count: 9 Strand: -
Coding Region
   Position: hg38 chr8:21,693,278-21,788,159 Size: 94,882 Coding Exon Count: 9 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther NamesMethods
Data last updated at UCSC: 2021-06-20 19:51:40

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr8:21,690,398-21,788,875)mRNA (may differ from genome)Protein (464 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaExonPrimerGeneCards
HGNCMGIPubMedUniProtKB

-  Comments and Description Text from UniProtKB
  ID: GFRA2_HUMAN
DESCRIPTION: RecName: Full=GDNF family receptor alpha-2; Short=GDNF receptor alpha-2; Short=GDNFR-alpha-2; Short=GFR-alpha-2; AltName: Full=GDNF receptor beta; Short=GDNFR-beta; AltName: Full=Neurturin receptor alpha; Short=NRTNR-alpha; Short=NTNR-alpha; AltName: Full=RET ligand 2; AltName: Full=TGF-beta-related neurotrophic factor receptor 2; Flags: Precursor;
FUNCTION: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor (By similarity).
TISSUE SPECIFICITY: Isoform 1 is found in both brain and placenta.
SIMILARITY: Belongs to the GDNFR family.

+  Protein Domain and Structure Information
  Press "+" in the title bar above to open this section.

+  Other Names for This Gene
  Press "+" in the title bar above to open this section.

+  Methods, Credits, and Use Restrictions
  Press "+" in the title bar above to open this section.