ID:KCNG3_HUMAN DESCRIPTION: RecName: Full=Potassium voltage-gated channel subfamily G member 3; AltName: Full=Voltage-gated potassium channel subunit Kv10.1; AltName: Full=Voltage-gated potassium channel subunit Kv6.3; FUNCTION: Potassium channel subunit. Modulates channel activity. SUBUNIT: Heteromultimer with KCNB1, KCNC1 and KCNF1. Does not form homomultimers. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1. TISSUE SPECIFICITY: Detected in many parts of the brain with the exception of the cerebellum, in testis, pancreas, lung, kidney, ovary, small intestine, colon, thymus, adrenal gland and spinal cord. DOMAIN: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position. SIMILARITY: Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.3/KCNG3 sub-subfamily.
Pfam Domains: PF00520 - Ion transport protein PF02214 - BTB/POZ domain
ModBase Predicted Comparative 3D Structure on Q8TAE7
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Other Names for This Gene
Press "+" in the title bar above to open this section.
Methods, Credits, and Use Restrictions
Press "+" in the title bar above to open this section.
