ID:ARP2_HUMAN DESCRIPTION: RecName: Full=Actin-related protein 2; AltName: Full=Actin-like protein 2; FUNCTION: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. SUBUNIT: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. Cell projection. SIMILARITY: Belongs to the actin family. ARP2 subfamily.
ModBase Predicted Comparative 3D Structure on P61160
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Other Names for This Gene
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Methods, Credits, and Use Restrictions
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