Human Gene MIA2 (ENST00000396158.6) Description and Page Index

Description: Homo sapiens MIA SH3 domain ER export factor 2 (MIA2), transcript variant 6, mRNA. (from RefSeq NM_001247989)
Gencode Transcript: ENST00000396158.6
Gencode Gene: ENSG00000150527.17
Transcript (Including UTRs)
Position: hg38 chr14:39,267,124-39,351,193 Size: 84,070 Total Exon Count: 24 Strand: +
Coding Region
Position: hg38 chr14:39,267,460-39,350,264 Size: 82,805 Coding Exon Count: 24

Page Index

Sequence and Links

UniProtKB Comments

Protein Structure

Other Names

Methods

Data last updated at UCSC: 2021-06-20 19:51:40

Comments and Description Text from UniProtKB


	ID: MIA2_HUMAN DESCRIPTION: RecName: Full=Melanoma inhibitory activity protein 2; Flags: Precursor; FUNCTION: May play a role in the pathophysiology of liver disease and may serve as a marker of liver damage. SUBCELLULAR LOCATION: Secreted (Potential). TISSUE SPECIFICITY: Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis. SIMILARITY: Belongs to the MIA/OTOR family. SIMILARITY: Contains 1 SH3 domain.

Protein Domain and Structure Information

InterPro Domains: Graphical view of domain structure
IPR011511 - SH3_2
IPR001452 - SH3_domain

Pfam Domains:
PF07653 - Variant SH3 domain

ModBase Predicted Comparative 3D Structure on Q96PC5


Front	Top	Side

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Other Names for This Gene


	UCSC ID: ENST00000396158.6 Representative RNA: NM_001247989 Protein: Q96PC5 (aka MIA2_HUMAN)