Human Gene TNNI1 (ENST00000336092.8) Description and Page Index
  Description: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (from UniProt P19237)
Gencode Transcript: ENST00000336092.8
Gencode Gene: ENSG00000159173.19
Transcript (Including UTRs)
   Position: hg38 chr1:201,408,864-201,429,866 Size: 21,003 Total Exon Count: 12 Strand: -
Coding Region
   Position: hg38 chr1:201,410,328-201,417,793 Size: 7,466 Coding Exon Count: 7 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther NamesMethods
Data last updated at UCSC: 2021-06-20 19:51:40

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:201,408,864-201,429,866)mRNA (may differ from genome)Protein (187 aa)
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-  Comments and Description Text from UniProtKB
  ID: TNNI1_HUMAN
DESCRIPTION: RecName: Full=Troponin I, slow skeletal muscle; AltName: Full=Troponin I, slow-twitch isoform;
FUNCTION: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
SUBUNIT: Binds to actin and tropomyosin.
TISSUE SPECIFICITY: Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes.
SIMILARITY: Belongs to the troponin I family.

+  Protein Domain and Structure Information
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+  Other Names for This Gene
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+  Methods, Credits, and Use Restrictions
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