Human Gene TRO (ENST00000319167.12) Description and Page Index

Description: Homo sapiens trophinin (TRO), transcript variant 3, mRNA. (from RefSeq NM_016157)
Gencode Transcript: ENST00000319167.12
Gencode Gene: ENSG00000067445.21
Transcript (Including UTRs)
Position: hg38 chrX:54,920,811-54,931,431 Size: 10,621 Total Exon Count: 13 Strand: +
Coding Region
Position: hg38 chrX:54,922,247-54,931,338 Size: 9,092 Coding Exon Count: 12

Page Index

Sequence and Links

UniProtKB Comments

Protein Structure

Other Names

Methods

Data last updated at UCSC: 2021-06-20 19:51:40

Comments and Description Text from UniProtKB


	ID: TROP_HUMAN DESCRIPTION: RecName: Full=Trophinin; AltName: Full=MAGE-D3 antigen; FUNCTION: Could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Directly responsible for homophilic cell adhesion. SUBUNIT: Directly binds bystin, and indirectly tastin. INTERACTION: Q13895:BYSL; NbExp=4; IntAct=EBI-950001, EBI-358049; TISSUE SPECIFICITY: Strong expression at implantation sites. Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decreased and then disappeared from placental villi. Also found in macrophages. SIMILARITY: Contains 1 MAGE domain. SEQUENCE CAUTION: Sequence=AAA79334.2; Type=Erroneous initiation; Sequence=BAA83066.3; Type=Erroneous initiation;