Human Gene MFSD6 (ENST00000392328.6) Description and Page Index

Description: Homo sapiens major facilitator superfamily domain containing 6 (MFSD6), transcript variant 2, mRNA. (from RefSeq NM_017694)
Gencode Transcript: ENST00000392328.6
Gencode Gene: ENSG00000151690.15
Transcript (Including UTRs)
Position: hg38 chr2:190,408,355-190,502,314 Size: 93,960 Total Exon Count: 8 Strand: +
Coding Region
Position: hg38 chr2:190,436,030-190,500,218 Size: 64,189 Coding Exon Count: 6

Page Index

Sequence and Links

UniProtKB Comments

Protein Structure

Other Names

Methods

Data last updated at UCSC: 2021-06-20 19:51:40

Comments and Description Text from UniProtKB


	ID: MFSD6_HUMAN DESCRIPTION: RecName: Full=Major facilitator superfamily domain-containing protein 6; AltName: Full=Macrophage MHC class I receptor 2 homolog; SUBUNIT: May interact with HLA-B62. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential). TISSUE SPECIFICITY: Widely expressed. Expression levels in peripheral blood mononuclear cells are highly variable between individuals, including no expression at all. SIMILARITY: Belongs to the major facilitator superfamily. MFSD6 family. SEQUENCE CAUTION: Sequence=AAY24173.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAA90987.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=EAX10868.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Protein Domain and Structure Information

InterPro Domains: Graphical view of domain structure
IPR011701 - MFS
IPR024989 - MFS_assoc_dom
IPR016196 - MFS_dom_general_subst_transpt

Pfam Domains:
PF07690 - Major Facilitator Superfamily
PF12832 - MFS_1 like family

ModBase Predicted Comparative 3D Structure on Q6ZSS7


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