Press "+" in the title bar above to open this section.
Comments and Description Text from UniProtKB
ID:TMIG2_HUMAN DESCRIPTION: RecName: Full=Transmembrane and immunoglobulin domain-containing protein 2; AltName: Full=Immunoglobulin and proline-rich receptor 1; Short=IGPR-1; Flags: Precursor; FUNCTION: Plays a role in cell-cell interaction, cell migration, and angiogenesis. SUBUNIT: May form homophilic interactions that could regulate cell-cell interaction. Interacts with CACNB2, DST, MIA and NCKIPSD. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Widely expressed, mainly by epithelial and endothelial cells, including bronchial epithelial cells of lung, breast glandular and lobular epithelia cells, urothelium of the bladder, skin epidermis, epithelium of gastrointestinal, rectum, endometrial glands of the uterus, ureter, fallopian tube epithelium, colonic epithelium, small bowl epithelium, stomach epithelium, including both chief and parietal cells, trophoblastic epithelium of placenta, and pancreatic acinar cells (at protein level). Consistently expressed in veins and arteries (at protein level). Not detected in thyroid, cerebellum, cerebral cortex and thymus (at protein level). PTM: N-glycosylated. SIMILARITY: Contains 1 Ig-like (immunoglobulin-like) domain.
ModBase Predicted Comparative 3D Structure on Q96BF3
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Other Names for This Gene
Press "+" in the title bar above to open this section.
Methods, Credits, and Use Restrictions
Click here
for details on how this gene model was made and data restrictions if any.
