Human Gene NFATC4 (ENST00000556279.5) Description and Page Index
Description: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL- 4. Transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons. (from UniProt Q14934) Gencode Transcript: ENST00000556279.5 Gencode Gene: ENSG00000100968.14 Transcript (Including UTRs) Position: hg38 chr14:24,367,468-24,377,705 Size: 10,238 Total Exon Count: 11 Strand: + Coding Region Position: hg38 chr14:24,367,587-24,377,705 Size: 10,119 Coding Exon Count: 11
ModBase Predicted Comparative 3D Structure on Q14934
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Other Names for This Gene
Press "+" in the title bar above to open this section.
Methods, Credits, and Use Restrictions
Click here
for details on how this gene model was made and data restrictions if any.