ID:BRD1_HUMAN DESCRIPTION: RecName: Full=Bromodomain-containing protein 1; AltName: Full=BR140-like protein; AltName: Full=Bromodomain and PHD finger-containing protein 2; FUNCTION: Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. SUBUNIT: Component of the MOZ/MORF complex composed at least of ING5, KAT6A, KAT6B, MEAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3. Interacts (via PHD-type zinc finger domain) with unmodified histone H3. Interacts (via PWWP domain) with dimethylated and trimethylated 'Lys-79' on histone H3. SUBCELLULAR LOCATION: Nucleus. TISSUE SPECIFICITY: Highly expressed in testis. SIMILARITY: Contains 1 bromo domain. SIMILARITY: Contains 1 PHD-type zinc finger. SIMILARITY: Contains 1 PWWP domain.
ModBase Predicted Comparative 3D Structure on O95696
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Other Names for This Gene
Press "+" in the title bar above to open this section.
Methods, Credits, and Use Restrictions
Click here
for details on how this gene model was made and data restrictions if any.
