Human Gene IL23R (ENST00000425614.3) Description and Page Index
Description: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. (from UniProt Q5VWK5) Gencode Transcript: ENST00000425614.3 Gencode Gene: ENSG00000162594.16 Transcript (Including UTRs) Position: hg38 chr1:67,207,616-67,259,248 Size: 51,633 Total Exon Count: 6 Strand: + Coding Region Position: hg38 chr1:67,207,666-67,259,128 Size: 51,463 Coding Exon Count: 6