Human Gene INSM1 (ENST00000310227.3) Description and Page Index

Description: Homo sapiens INSM transcriptional repressor 1 (INSM1), mRNA. (from RefSeq NM_002196)
Gencode Transcript: ENST00000310227.3
Gencode Gene: ENSG00000173404.5
Transcript (Including UTRs)
Position: hg38 chr20:20,368,104-20,370,949 Size: 2,846 Total Exon Count: 1 Strand: +
Coding Region
Position: hg38 chr20:20,368,268-20,369,800 Size: 1,533 Coding Exon Count: 1

Page Index

Sequence and Links

UniProtKB Comments

Protein Structure

Other Names

Methods

Data last updated at UCSC: 2021-06-20 19:51:40

Comments and Description Text from UniProtKB


	ID: INSM1_HUMAN DESCRIPTION: RecName: Full=Insulinoma-associated protein 1; AltName: Full=Zinc finger protein IA-1; FUNCTION: May be associated with the transformation of neuroendocrine cells. SUBCELLULAR LOCATION: Nucleus (Potential). TISSUE SPECIFICITY: Several tumor cell lines of neuroendocrine origin including pheochromocytoma, medullary thyroid carcinoma, insulinoma, pituitary tumor, and small cell lung carcinoma. Not found in any of the normal tissues tested. SIMILARITY: Contains 5 C2H2-type zinc fingers.

Protein Domain and Structure Information

InterPro Domains: Graphical view of domain structure
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd

Pfam Domains:
PF00096 - Zinc finger, C2H2 type

Protein Data Bank (PDB) 3-D Structure
MuPIT help

2LV2 - NMR

ModBase Predicted Comparative 3D Structure on Q01101


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