Human Gene FOXP4 (ENST00000307972.9) Description and Page Index
Description: Homo sapiens forkhead box P4 (FOXP4), transcript variant 1, mRNA. (from RefSeq NM_001012426)Gencode Transcript: ENST00000307972.9Gencode Gene: ENSG00000137166.16Transcript (Including UTRs) Position: hg38 chr6:41,546,426-41,600,626 Size: 54,201 Total Exon Count: 17 Strand: +Coding Region Position: hg38 chr6:41,565,761-41,598,936 Size: 33,176 Coding Exon Count: 16
Data last updated at UCSC: 2021-06-20 19:51:40
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: FOXP4_HUMAN DESCRIPTION: RecName: Full=Forkhead box protein P4; AltName: Full=Fork head-related protein-like A;FUNCTION: Transcriptional repressor that represses lung-specific expression (By similarity).SUBUNIT: Forms homodimers and heterodimers with FOXP1 and FOXP2. Dimerization is required for DNA-binding (By similarity).SUBCELLULAR LOCATION: Nucleus (Potential).DOMAIN: The leucine-zipper is required for dimerization and transcriptional repression (By similarity).SIMILARITY: Contains 1 C2H2-type zinc finger.SIMILARITY: Contains 1 fork-head DNA-binding domain.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR001766 - TF_fork_headIPR018122 - TF_fork_head_CSIPR011991 - WHTH_trsnscrt_rep_DNA-bdIPR015880 - Znf_C2H2-likePfam Domains: PF00250 - Forkhead domainModBase Predicted Comparative 3D Structure on Q8IVH2 The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Other Names for This Gene
UCSC ID: ENST00000307972.9Representative RNA: NM_001012426 Protein: Q8IVH2
(aka FOXP4_HUMAN or FXP4_HUMAN)
Methods, Credits, and Use Restrictions
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