Human Gene SLC6A4 (ENST00000261707.7) Description and Page Index
  Description: Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner. (from UniProt P31645)
Gencode Transcript: ENST00000261707.7
Gencode Gene: ENSG00000108576.10
Transcript (Including UTRs)
   Position: hg38 chr17:30,194,321-30,235,968 Size: 41,648 Total Exon Count: 15 Strand: -
Coding Region
   Position: hg38 chr17:30,198,456-30,221,958 Size: 23,503 Coding Exon Count: 13 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther NamesMethods
Data last updated at UCSC: 2021-06-20 19:51:40

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:30,194,321-30,235,968)mRNA (may differ from genome)Protein (630 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaExonPrimerGeneCards
HGNCMGIPubMedUniProtKB

+  Comments and Description Text from UniProtKB
  Press "+" in the title bar above to open this section.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000175 - Na/ntran_symport
IPR013086 - Na/ntran_symport_serotonin_N

Pfam Domains:
PF03491 - Serotonin (5-HT) neurotransmitter transporter, N-terminus
PF00209 - Sodium:neurotransmitter symporter family

ModBase Predicted Comparative 3D Structure on P31645
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

+  Other Names for This Gene
  Press "+" in the title bar above to open this section.

+  Methods, Credits, and Use Restrictions
  Press "+" in the title bar above to open this section.