Human Gene NFATC4 (ENST00000556279.5) Description and Page Index
Description: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL- 4. Transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons. (from UniProt Q14934) Gencode Transcript: ENST00000556279.5 Gencode Gene: ENSG00000100968.14 Transcript (Including UTRs) Position: hg38 chr14:24,367,468-24,377,705 Size: 10,238 Total Exon Count: 11 Strand: + Coding Region Position: hg38 chr14:24,367,587-24,377,705 Size: 10,119 Coding Exon Count: 11