Human Gene LDHC (ENST00000541669.6) Description and Page Index

Description: Homo sapiens lactate dehydrogenase C (LDHC), transcript variant 2, mRNA. (from RefSeq NM_017448)
Gencode Transcript: ENST00000541669.6
Gencode Gene: ENSG00000166796.12
Transcript (Including UTRs)
Position: hg38 chr11:18,412,318-18,452,063 Size: 39,746 Total Exon Count: 8 Strand: +
Coding Region
Position: hg38 chr11:18,412,718-18,451,127 Size: 38,410 Coding Exon Count: 7

Page Index

Sequence and Links

UniProtKB Comments

Protein Structure

Other Names

Methods

Data last updated at UCSC: 2021-06-20 19:51:40

Comments and Description Text from UniProtKB


	ID: LDHC_HUMAN DESCRIPTION: RecName: Full=L-lactate dehydrogenase C chain; Short=LDH-C; EC=1.1.1.27; AltName: Full=Cancer/testis antigen 32; Short=CT32; AltName: Full=LDH testis subunit; AltName: Full=LDH-X; FUNCTION: Possible role in sperm motility. CATALYTIC ACTIVITY: (S)-lactate + NAD(+) = pyruvate + NADH. PATHWAY: Fermentation; pyruvate fermentation to lactate; (S)- lactate from pyruvate: step 1/1. SUBUNIT: Homotetramer. SUBCELLULAR LOCATION: Cytoplasm. SIMILARITY: Belongs to the LDH/MDH superfamily. LDH family. WEB RESOURCE: Name=GeneReviews; URL="http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/LDHC"; WEB RESOURCE: Name=Wikipedia; Note=Lactate dehydrogenase entry; URL="http://en.wikipedia.org/wiki/Lactate_dehydrogenase";

Protein Domain and Structure Information

InterPro Domains: Graphical view of domain structure
IPR001557 - L-lactate/malate_DH
IPR011304 - L-lactate_DH
IPR018177 - L-lactate_DH_AS
IPR022383 - Lactate/malate_DH_C
IPR001236 - Lactate/malate_DH_N
IPR015955 - Lactate_DH/Glyco_Ohase_4_C
IPR016040 - NAD(P)-bd_dom

Pfam Domains:
PF02866 - lactate/malate dehydrogenase, alpha/beta C-terminal domain
PF00056 - lactate/malate dehydrogenase, NAD binding domain

ModBase Predicted Comparative 3D Structure on P07864


Front	Top	Side

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