Human Gene SETD1B (ENST00000619791.1) Description and Page Index
  Description: Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys- 9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro. (from UniProt Q9UPS6)
Gencode Transcript: ENST00000619791.1
Gencode Gene: ENSG00000139718.11
Transcript (Including UTRs)
   Position: hg38 chr12:121,804,738-121,830,239 Size: 25,502 Total Exon Count: 16 Strand: +
Coding Region
   Position: hg38 chr12:121,804,738-121,830,239 Size: 25,502 Coding Exon Count: 16 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther NamesMethods
Data last updated at UCSC: 2021-06-20 19:51:40

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:121,804,738-121,830,239)mRNA (may differ from genome)Protein (1966 aa)
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+  Comments and Description Text from UniProtKB
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+  Protein Domain and Structure Information
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+  Other Names for This Gene
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+  Methods, Credits, and Use Restrictions
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