ID:TROP_HUMAN DESCRIPTION: RecName: Full=Trophinin; AltName: Full=MAGE-D3 antigen; FUNCTION: Could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Directly responsible for homophilic cell adhesion. SUBUNIT: Directly binds bystin, and indirectly tastin. INTERACTION: Q13895:BYSL; NbExp=4; IntAct=EBI-950001, EBI-358049; TISSUE SPECIFICITY: Strong expression at implantation sites. Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decreased and then disappeared from placental villi. Also found in macrophages. SIMILARITY: Contains 1 MAGE domain. SEQUENCE CAUTION: Sequence=AAA79334.2; Type=Erroneous initiation; Sequence=BAA83066.3; Type=Erroneous initiation;
ModBase Predicted Comparative 3D Structure on Q12816
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
