Human Gene VHLL (ENST00000339922.5) Description and Page Index
  Description: Homo sapiens VHL like (VHLL), mRNA. (from RefSeq NM_001004319)
Gencode Transcript: ENST00000339922.5
Gencode Gene: ENSG00000189030.10
Transcript (Including UTRs)
   Position: hg38 chr1:156,298,624-156,299,307 Size: 684 Total Exon Count: 1 Strand: -
Coding Region
   Position: hg38 chr1:156,298,770-156,299,189 Size: 420 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther NamesMethods
Data last updated at UCSC: 2021-06-20 19:51:40

+  Sequence and Links to Tools and Databases
  Press "+" in the title bar above to open this section.

-  Comments and Description Text from UniProtKB
  ID: VHLL_HUMAN
DESCRIPTION: RecName: Full=Von Hippel-Lindau-like protein; Short=VHL-like protein; Short=VLP;
FUNCTION: Functions as a dominant-negative VHL to serve as a protector of HIFalpha.
SUBUNIT: Interacts via the beta domain with the ODD domain of HIF1A This interaction is independent of prolyl hydroxylation of HIF1A.
TISSUE SPECIFICITY: Abundantly expressed in the placenta.
MISCELLANEOUS: Has little or no E3 ubiquitin ligase activity as it lacks the alpha domain required for nucleating the multiprotein E3 ubiquitin ligase complex.

+  Protein Domain and Structure Information
  Press "+" in the title bar above to open this section.

+  Other Names for This Gene
  Press "+" in the title bar above to open this section.

+  Methods, Credits, and Use Restrictions
  Press "+" in the title bar above to open this section.