Human Gene KCNG3 (ENST00000306078.2) Description and Page Index

Description: Homo sapiens potassium voltage-gated channel modifier subfamily G member 3 (KCNG3), transcript variant 1, mRNA. (from RefSeq NM_133329)
Gencode Transcript: ENST00000306078.2
Gencode Gene: ENSG00000171126.8
Transcript (Including UTRs)
Position: hg38 chr2:42,442,017-42,493,982 Size: 51,966 Total Exon Count: 2 Strand: -
Coding Region
Position: hg38 chr2:42,443,934-42,493,501 Size: 49,568 Coding Exon Count: 2

Page Index

Sequence and Links

UniProtKB Comments

Protein Structure

Other Names

Methods

Data last updated at UCSC: 2021-06-20 19:51:40

Comments and Description Text from UniProtKB


	ID: KCNG3_HUMAN DESCRIPTION: RecName: Full=Potassium voltage-gated channel subfamily G member 3; AltName: Full=Voltage-gated potassium channel subunit Kv10.1; AltName: Full=Voltage-gated potassium channel subunit Kv6.3; FUNCTION: Potassium channel subunit. Modulates channel activity. SUBUNIT: Heteromultimer with KCNB1, KCNC1 and KCNF1. Does not form homomultimers. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1. TISSUE SPECIFICITY: Detected in many parts of the brain with the exception of the cerebellum, in testis, pancreas, lung, kidney, ovary, small intestine, colon, thymus, adrenal gland and spinal cord. DOMAIN: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position. SIMILARITY: Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.3/KCNG3 sub-subfamily.