Human Gene GRB2 (ENST00000392564.5) Description and Page Index
  Description: Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. (from UniProt P62993)
Gencode Transcript: ENST00000392564.5
Gencode Gene: ENSG00000177885.15
Transcript (Including UTRs)
   Position: hg38 chr17:75,318,076-75,393,864 Size: 75,789 Total Exon Count: 5 Strand: -
Coding Region
   Position: hg38 chr17:75,320,368-75,393,628 Size: 73,261 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther NamesMethods
Data last updated at UCSC: 2021-06-20 19:51:40

+  Sequence and Links to Tools and Databases
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+  Comments and Description Text from UniProtKB
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-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000108 - p67phox
IPR000980 - SH2
IPR001452 - SH3_domain

Pfam Domains:
PF00017 - SH2 domain
PF00018 - SH3 domain

Protein Data Bank (PDB) 3-D Structure
MuPIT help

1AZE
- NMR

1BM2
- X-ray

1BMB
- X-ray
To conserve bandwidth, only the images from the first 3 structures are shown.
1CJ1 - X-ray 1FHS - NMR 1FYR - X-ray
1GCQ - X-ray 1GFC - NMR 1GFD - NMR
1GHU - NMR 1GRI - X-ray 1IO6 - NMR
1JYQ - X-ray 1JYR - X-ray 1JYU - X-ray
1QG1 - NMR 1TZE - X-ray 1X0N - NMR
1ZFP - X-ray 2AOA - X-ray 2AOB - X-ray
2H46 - X-ray 2H5K - X-ray 2HUW - X-ray
2VVK - X-ray 2VWF - X-ray 2W0Z - X-ray
3C7I - X-ray 3IMD - X-ray 3IMJ - X-ray
3IN7 - X-ray 3IN8 - X-ray 3KFJ - X-ray
3MXC - X-ray 3MXY - X-ray 3N7Y - X-ray
3N84 - X-ray 3N8M - X-ray 3OV1 - X-ray
3OVE - X-ray 3S8L - X-ray 3S8N - X-ray
3S8O - X-ray


ModBase Predicted Comparative 3D Structure on P62993
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-  Other Names for This Gene
  UCSC ID: ENST00000392564.5
Representative RNA: AK091010
Protein: P62993 (aka GRB2_HUMAN)

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.