Human Gene C1S (ENST00000406697.5) Description and Page Index
  Description: C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. (from UniProt P09871)
Gencode Transcript: ENST00000406697.5
Gencode Gene: ENSG00000182326.15
Transcript (Including UTRs)
   Position: hg38 chr12:6,988,259-7,071,032 Size: 82,774 Total Exon Count: 15 Strand: +
Coding Region
   Position: hg38 chr12:7,061,913-7,070,651 Size: 8,739 Coding Exon Count: 11 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther NamesMethods
Data last updated at UCSC: 2021-06-20 19:51:40

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:6,988,259-7,071,032)mRNA (may differ from genome)Protein (688 aa)
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+  Comments and Description Text from UniProtKB
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-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR016060 - Complement_control_module
IPR000859 - CUB
IPR001881 - EGF-like_Ca-bd
IPR000152 - EGF-type_Asp/Asn_hydroxyl_site
IPR018097 - EGF_Ca-bd_CS
IPR009003 - Pept_cys/ser_Trypsin-like
IPR024175 - Pept_S1A_C1r/C1S/mannan-bd
IPR018114 - Peptidase_S1/S6_AS
IPR001254 - Peptidase_S1_S6
IPR001314 - Peptidase_S1A
IPR000436 - Sushi_SCR_CCP

Pfam Domains:
PF00431 - CUB domain
PF07645 - Calcium-binding EGF domain
PF00084 - Sushi repeat (SCR repeat)
PF00089 - Trypsin

Protein Data Bank (PDB) 3-D Structure
MuPIT help

1ELV
- X-ray

1NZI
- X-ray


ModBase Predicted Comparative 3D Structure on P09871
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+  Other Names for This Gene
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+  Methods, Credits, and Use Restrictions
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