Human Gene TP53 (ENST00000610292.4) Description and Page Index
  Description: Homo sapiens tumor protein p53 (TP53), transcript variant 8, mRNA. (from RefSeq NM_001126118)
Gencode Transcript: ENST00000610292.4
Gencode Gene: ENSG00000141510.18
Transcript (Including UTRs)
   Position: hg38 chr17:7,668,402-7,687,481 Size: 19,080 Total Exon Count: 10 Strand: -
Coding Region
   Position: hg38 chr17:7,669,609-7,676,251 Size: 6,643 Coding Exon Count: 8 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther NamesMethods
Data last updated at UCSC: 2021-06-20 19:51:40

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:7,668,402-7,687,481)mRNA (may differ from genome)Protein (354 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaExonPrimerGeneCards
HGNCMGIPubMedUniProtKB

+  Comments and Description Text from UniProtKB
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-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR008967 - p53-like_TF_DNA-bd
IPR012346 - p53/RUNT-type_TF_DNA-bd
IPR011615 - p53_DNA-bd
IPR010991 - p53_tetrameristn
IPR013872 - p53_transactivation_domain
IPR002117 - p53_tumour_suppressor

Pfam Domains:
PF00870 - P53 DNA-binding domain
PF08563 - P53 transactivation motif
PF07710 - P53 tetramerisation motif

Protein Data Bank (PDB) 3-D Structure
MuPIT help

1A1U
- NMR

1AIE
- X-ray

1C26
- X-ray
To conserve bandwidth, only the images from the first 3 structures are shown.
1DT7 - NMR 1GZH - X-ray 1H26 - X-ray
1HS5 - NMR 1JSP - NMR 1KZY - X-ray
1MA3 - X-ray 1OLG - NMR 1OLH - NMR
1PES - NMR 1PET - NMR 1SAE - NMR
1SAF - NMR 1SAK - NMR 1SAL - NMR
1TSR - X-ray 1TUP - X-ray 1UOL - X-ray
1XQH - X-ray 1YC5 - X-ray 1YCQ - X-ray
1YCR - X-ray 1YCS - X-ray 2AC0 - X-ray
2ADY - X-ray 2AHI - X-ray 2ATA - X-ray
2B3G - X-ray 2BIM - X-ray 2BIN - X-ray
2BIO - X-ray 2BIP - X-ray 2BIQ - X-ray
2F1X - X-ray 2FEJ - NMR 2FOJ - X-ray
2FOO - X-ray 2GS0 - NMR 2H1L - X-ray
2H2D - X-ray 2H2F - X-ray 2H4F - X-ray
2H4H - X-ray 2H4J - X-ray 2H59 - X-ray
2J0Z - NMR 2J10 - NMR 2J11 - NMR
2J1W - X-ray 2J1X - X-ray 2J1Y - X-ray
2J1Z - X-ray 2J20 - X-ray 2J21 - X-ray
2K8F - NMR 2L14 - NMR 2OCJ - X-ray
2PCX - X-ray 2QVQ - X-ray 2QXA - X-ray
2QXB - X-ray 2QXC - X-ray 2VUK - X-ray
2WGX - X-ray 2X0U - X-ray 2X0V - X-ray
2X0W - X-ray 2XWR - X-ray 2YBG - X-ray
2Z5S - X-ray 2Z5T - X-ray 3D05 - X-ray
3D06 - X-ray 3D07 - X-ray 3D08 - X-ray
3D09 - X-ray 3D0A - X-ray 3DAB - X-ray
3DAC - X-ray 3IGK - X-ray 3IGL - X-ray
3KMD - X-ray 3KZ8 - X-ray 3LW1 - X-ray
3OQ5 - X-ray 3PDH - X-ray 3Q01 - X-ray
3Q05 - X-ray 3Q06 - X-ray 3SAK - NMR
3TG5 - X-ray 3TS8 - X-ray 4AGL - X-ray
4AGM - X-ray 4AGN - X-ray 4AGO - X-ray
4AGP - X-ray 4AGQ - X-ray


ModBase Predicted Comparative 3D Structure on P04637
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

+  Other Names for This Gene
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-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.