Human Gene SERPINA1 (ENST00000404814.8) Description and Page Index
Description: Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. (from UniProt P01009) Gencode Transcript: ENST00000404814.8 Gencode Gene: ENSG00000197249.14 Transcript (Including UTRs) Position: hg38 chr14:94,378,389-94,390,662 Size: 12,274 Total Exon Count: 6 Strand: - Coding Region Position: hg38 chr14:94,378,449-94,383,237 Size: 4,789 Coding Exon Count: 4
ModBase Predicted Comparative 3D Structure on P01009
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
